Betamethasone


Betamethasone

Specifications

CAS Number 378-44-9
MOL. Formula C22H29FO5
MOL.Weight 392.46
Standard Offered of pharmaceutical grade bp/usp/ep
Packing Offered in export worthy packing of 25 kilos or as per our customer requirements
Elimination half-life 36-54 hours
Supplied By UMA Brothers, India

Betamethasone is a corticosteroid. The mechanism of action of betamethasone is as a corticosteroid hormone receptor agonist. Betamethasone is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to dna to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia.

Betamethasone Is A White To Off-White Solid. It Is Soluble In Methanol With Melting Range Of 231°C To 234°C.

Synonyms
(8s,9r,10s,11s,13s,14s,16s,17r)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahy drocyclopenta [a]phenanthren-3-one


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