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Quetiapine is a dibenzothiazepine and antipsychotic agent that targets the serotonin 5-ht2 receptor; histamine h1 receptor, adrenergic alpha1 and alpha2 receptors, as well as the dopamine d1 receptor and dopamine d2 receptor. It is used in the treatment of schizophrenia; bipolar disorder & depressive disorder. Quetiapine is an atypical antipsychotic.
Quetiapine is a dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-ht 1a and 5-ht2 receptors. With a lower affinity, this agent also reversibly binds to dopamine d1 and d2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine h1 receptors.
Quetiapine Is White Solid Powder. It Is Soluble In Dmso, And Water With Melting Point Of 223.40°C.