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Specifications
Synonyms | Silver; (4-AMINOPHENYL) Sulfonyl-Pyrimidin-2-Ylazanide |
Cas Number | 22199-08-2 |
Mol. Formula | C10H9AGN4O2S |
Mol.weight | 357.14 |
Standard | Offered of Pharmaceutical Grade BP/USP/EP |
Packing | Offered in Export Worthy Packing of 5/10/25 Kilos or as per Our Customer Requirements |
Supplied By | UMA Brothers, India |
Silver sulfadiazine is a sulfonamide antibacterial. The chemical classification of silver sulfadiazine is sulfonamides. Sulfadiazine silver is a sulfonamide-based topical agent with antibacterial & antifungal activity. silver sulfadiazine may act through a combination of the activity of silver & sulfadiazine. When this agent interacts with sodium chloride-containing body fluids, silver ions are released slowly and sustainably into wounded areas. Ionized silver atoms catalyze the formation of disulfide bonds leading to protein structural changes and inactivating thiol-containing enzymes; silver ions may also intercalate dna thereby interfering with replication and transcription of bacteria. As a competitive inhibitor of para-aminobenzoic acid (paba), sulfadiazine inhibits bacterial dihydropteroate synthase, thereby resulting in disruption of folic acid metabolism and ultimately dna synthesis.
Silver sulfadiazine is a crystalline solid. It is soluble in water with melting range of 282°C t0 284°C.